Illinois vs. Wyoming odds, line: 2022 college football picks, Model Week 0 predictions on 43-31 run


The Wyoming Cowboys and Illinois Fighting Illini will face off in a Saturday afternoon contest in Week 0 of the 2022 college football season. The Cowboys are 4-1 ATS at their last five games overall. On the other hand, the Fighting Illini are 2-5 ATS in their last seven games in August. Wyoming was 7-6 in 2021 but suffered heavy losses in the transfer gate. Illinois went 5-7 in Bret Bielema’s freshman season last year.

Kickoff from Memorial Stadium in Champaign, Ill., is scheduled for 4 p.m. ET. After opening at -9.5, the Fighting Illini are now -14 in the latest Wyoming vs. Illinois odds at Caesars Sportsbook. The over/under for total points is set at 43. Before you lock in Illinois vs. Wyoming picks or college football predictions, you need to see what the SportsLine projection model has to say.

The model simulates every FBS college football game 10,000 times. Over the past six years, the proprietary computer model has generated an astonishing profit of nearly $3,600 for $100 players on its top-rated college football picks against the spread. He also finished the 2021-22 college football season on a 43-31 run on all college football top picks. Everyone who followed him saw huge returns.

Now the model has set its sights on Illinois vs. Wyoming and has just locked in its picks and predictions on the BFC. You can visit SportsLine now to see the model choices. Here are the college football odds and betting lines for Wyoming vs. Illinois:

  • Illinois vs. Wyoming Spread: Fighting Illini -14
  • Illinois vs. Wyoming over/under: 43 points
  • Illinois vs. Wyoming silver line: Fighting Illini -650, Cowboys +460
  • WYO: Over bets are 5-1 in Cowboys’ last six games
  • ILL: Fighting Illini is 4-1 ATS in its last five games overall
  • Illinois vs. Wyoming pick: See the picks on SportsLine

Featured game | Illinois Fighting Illini vs. Wyoming Cowboys

Why Wyoming Can Cover

Second-year linebacker Easton Gibbs will be a physical anchor in the middle of this defensive unit. Gibbs is a quick and powerful force with terrific reaction time. The California native has formed an outstanding duo with 2022 third-round pick Chad Muma. As a freshman, Gibbs was second on the team in total tackles (89) with four pass deflections.

Nose tackle Cole Godbout is a big offensive presence on the defensive line. Godbout could consistently beat his man and get into the backfield. The Wisconsin native finished the campaign third on the team in total tackles (70), tied for second in the TFL (7) and first in sacks (5). He was also raising his hand at the line of scrimmage, suppressing five passes.

Why Illinois Can Cover

Illinois will be looking to establish the ground attack in this contest. If the Illini can get things done, they can dial in shots deep down the court. This team averaged 173.6 rushing yards per game in the 2021 season. Sophomore running back Josh McCray plays a nice role in that rushing game. McCray was second on the team with 112 carries for 549 yards and two scores.

The Alabama native displayed good vision with solid speed. He rushed for over 100 yards in two games last season, including a monster performance against Purdue. McCray recorded 24 carries for 156 yards with 6.5 yards per carry. If they can get this running game going, it will allow everything else in the offense to open up.

How to Make Wyoming vs. Illinois Picks

SportsLine’s model leans into the total, projecting a combined 45 points. It also indicates that one side of the spread hits well over 60% of the time. You can only get the model choice at SportsLine.

So who wins Illinois against Wyoming? And which side of the spread hits well over 60% of the time? Visit SportsLine now to see which side of the spread to fall back to, all from the advanced model that rose nearly $3,600 on its top-rated college football spread picks, and find out.


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